Chronic Constipation Unmasked: A Comprehensive Case Study of Colonic Inertia and Its Future Implications

Cureus. 2024 May 10;16(5):e60031. doi: 10.7759/cureus.60031. eCollection 2024 May.

Abstract

Colonic inertia is a gastrointestinal disorder characterized by a significant delay in colon transit, resulting in chronic constipation that impedes an undisclosed percentage of individuals in the United States. This article aims to delve into the intricate mechanisms underlying the hindered transit observed in colonic inertia, focusing on multifactorial etiology and treatment. By gaining a better understanding of the pathophysiology of colonic inertia, we can improve the quality of life for individuals affected by this condition. Our study employs a comprehensive approach, combining clinical observation during pancolectomy, histopathological analyses performed by pathologists, and detailed investigation to unravel the complex interplay of factors affecting colonic motility.

Keywords: chronic abdominal pain; colonic inertia; colonic motility; constipation; gastrointestinal disease; subtotal colectomy with ileostomy.

Publication types

  • Case Reports