Detection of herpes simplex infection in cytologic smears

Arch Pathol Lab Med. 1985 May;109(5):464-5.

Abstract

We compare the results of direct immunofluorescence (IF) with cytology (Papanicolaou's stains) for diagnosis of herpes simplex infection. Thirty smears were examined. Yellow-green fluorescence was seen in 17 smears. Only eight of these smears had diagnostic cytology, and nine of the smears with positive fluorescence had none (four) to minimal (five) cytologic changes, suggesting that direct IF is a much more sensitive method for diagnosis of herpes simplex infection in cytologic smears.

Publication types

  • Comparative Study

MeSH terms

  • Cytodiagnosis
  • Female
  • Fluorescent Antibody Technique*
  • Herpes Genitalis / diagnosis
  • Herpes Simplex / diagnosis*
  • Humans
  • Male
  • Vaginal Smears