Addressing the Historic Challenges of BRCA1 and BRCA2 Variant Curation and the Need for More Diverse Representation

JCO Clin Cancer Inform. 2024 Jun:8:e2400076. doi: 10.1200/CCI.24.00076.


Advancements in variant curation challenges: minority representation and incomplete data reporting.

Publication types

  • Editorial

MeSH terms

  • BRCA1 Protein* / genetics
  • BRCA2 Protein* / genetics
  • Breast Neoplasms / genetics
  • Databases, Genetic
  • Female
  • Genetic Predisposition to Disease
  • Genetic Variation*
  • Humans


  • BRCA1 Protein
  • BRCA2 Protein
  • BRCA1 protein, human
  • BRCA2 protein, human