Obsessive-compulsive disorder

Psychiatr Clin North Am. 1985 Mar;8(1):105-17.

Abstract

Obsessive-compulsive disorder is a heterogeneous cluster of syndromes that share aspects of both anxiety and affective disorders. Obsessive-compulsive disorder is epidemiologically and phenomenologically distinct from the compulsive character. Although both genetic and neuropsychological data suggest some biologic basis to obsessive-compulsive disorder, there is still insufficient information in both of these areas. Treatment with clomipramine, a tricyclic antidepressant, has proved useful for obsessional patients either as an adjunct to behavior therapy or as a primary treatment for patients who are not amenable to behavioral interventions.

Publication types

  • Clinical Trial
  • Review

MeSH terms

  • Antidepressive Agents, Tricyclic / therapeutic use
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / psychology
  • Anxiety Disorders / therapy
  • Behavior Therapy
  • Clinical Trials as Topic
  • Clomipramine / therapeutic use
  • Combined Modality Therapy
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology
  • Depressive Disorder / therapy
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Obsessive-Compulsive Disorder / diagnosis*
  • Obsessive-Compulsive Disorder / psychology
  • Obsessive-Compulsive Disorder / therapy
  • Psychological Tests

Substances

  • Antidepressive Agents, Tricyclic
  • Clomipramine