We report a patient with nonimmune fetal hydrops and multiple pathologic fractures. RNA analysis revealed a novel PIEZO1 variant. This report is the first to elucidate PIEZO1's role as a critical regulator of bone mass and strength.
Keywords: chylothorax, congenital; fractures, spontaneous; lymphedema; mechanoreceptors; military medicine; radionuclide imaging.
© 2024 The Author(s). Clinical Case Reports published by John Wiley & Sons Ltd.