The efficacy of lower axillary sampling in obtaining lymph node status in breast cancer: a controlled randomized trial

Br J Surg. 1985 May;72(5):368-9. doi: 10.1002/bjs.1800720512.


Four hundred and seventeen patients with operable breast cancer treated by simple mastectomy were randomly allocated to have node sampling or total axillary clearance. There was no significant difference in the incidence of node positivity. One hundred and thirty-five patients had node sampling and were randomized at the completion of this procedure to have axillary clearance or to have no further surgery. All node positive patients who went on to have a clearance had positive samples, confirming the accuracy of the sampling technique.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Clinical Trials as Topic
  • Female
  • Humans
  • Lymph Nodes / pathology*
  • Lymph Nodes / surgery
  • Mastectomy
  • Random Allocation