A Case of Superficial Kaposiform Hemangioendothelioma Treated with Oral Propranolol Combined with Topical Sirolimus

Vasc Health Risk Manag. 2024 Jun 12:20:251-254. doi: 10.2147/VHRM.S461505. eCollection 2024.

Abstract

Kaposiform hemangioendothelioma(KHE) without Kasabach-Merritt phenomenon is a rare tumor primarily observed in pediatric patients; however, its documentation in the literature remains limited. We reported about a 1-year-old boy diagnosed with superficial KHE who received oral propranolol in combination with topical sirolimus and reviewed relevant reports and treatment of superficial KHE.

Keywords: case treatment; pediatric patients; rare tumor; superficial kaposiform hemangioendothelioma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Administration, Oral
  • Biopsy
  • Hemangioendothelioma* / diagnosis
  • Hemangioendothelioma* / drug therapy
  • Humans
  • Infant
  • Kasabach-Merritt Syndrome
  • Male
  • Propranolol* / administration & dosage
  • Propranolol* / therapeutic use
  • Sarcoma, Kaposi* / drug therapy
  • Sarcoma, Kaposi* / pathology
  • Sirolimus* / administration & dosage
  • Treatment Outcome

Substances

  • Propranolol
  • Sirolimus

Supplementary concepts

  • Kaposiform Hemangioendothelioma