Nine patients with renal insufficiency in the terminal stage, 6 with chronic diffuse glomerulonephritis and 3 with chronic pyelonephritis, underwent 402 sessions of programmed hemodialysis. All the patients had persistent high arterial hypertension, which did not yield to conventional medical treatment, complicating hemodialysis extremely, as the procedure produced a critical increase of arterial blood pressure (ABP). The patients were given new hypotensive drugs (minoxidyl, captopril, prazosine), which lowered ABP and permitted a reduction of hypotensive injections during hemodialysis. Three patients were subjected to bilateral nephrectomy, which also considerably facilitated hemodialysis in these patients.