Papaya Leaf Extract Elevates Platelet Levels in Individuals With Dengue Fever

Cureus. 2024 May 26;16(5):e61090. doi: 10.7759/cureus.61090. eCollection 2024 May.

Abstract

Dengue, an arboviral illness, is notorious for inducing thrombocytopenia, leading to bleeding and heightened mortality risk. Carica papaya leaf extract has shown efficacy in elevating platelet counts. A 35-year-old male presented with fever, fatigue, and body pain persisting for four days. Additionally, he complained of severe back pain, ocular discomfort, and brief episodes of nosebleeds. Testing revealed a positive NS1 antigen, prompting the initiation of intravenous normal saline, paracetamol, and papaya extract tablets. Despite initial platelet levels of 74,000, a subsequent decline to 30,650 was observed following another nosebleed. Subsequently, the patient's spouse administered freshly prepared papaya leaf extract orally three to four times daily, resulting in a platelet count of 120,320 on day 14. Timely recognition of declining platelet levels and the commencement of C. Papaya leaf extract contributed significantly to averting mortality risks.

Keywords: acute dengue; carica papaya (c. papaya) extract; carica papaya leaf extract; carica papaya seeds; dengue fever/complications; dengue thrombocytopenia; high fever; natural medicine; non-severe dengue; thrombocytopenia.

Publication types

  • Case Reports