MUC5B
Idiopathic Pulmonary Fibrosis Risk Variant Promotes a Mucosecretory Phenotype and Loss of Small Airway Secretory Cells
Am J Respir Crit Care Med
.
2024 Aug 15;210(4):517-521.
doi: 10.1164/rccm.202311-2111LE.
Authors
Jonathan S Kurche
1
2
,
Carlyne D Cool
3
4
,
Rachel Z Blumhagen
5
,
Evgenia Dobrinskikh
6
,
David Heinz
4
,
Jeremy A Herrera
2
,
Ivana V Yang
2
7
,
David A Schwartz
8
2
Affiliations
1
Geriatric Research, Education, and Clinical Center, and.
2
Division of Pulmonary Sciences and Critical Care Medicine.
3
Department of Pathology.
4
Pathology Laboratory and.
5
Center for Genes, Environment, and Health, National Jewish Health, Denver, Colorado.
6
Perinatal Research Center, and.
7
Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
8
Research Division, Rocky Mountain Regional Veterans Administration Medical Center, Aurora, Colorado.
PMID:
38924494
PMCID:
PMC11351810
(available on
2025-08-15
)
DOI:
10.1164/rccm.202311-2111LE
No abstract available
Publication types
Letter
MeSH terms
Aged
Female
Humans
Idiopathic Pulmonary Fibrosis* / genetics
Male
Middle Aged
Mucin-5B* / genetics
Phenotype*
Substances
Mucin-5B
MUC5B protein, human
Grants and funding
P01-HL162607/HL/NHLBI NIH HHS/United States
R01 HL158668/HL/NHLBI NIH HHS/United States
UH3 HL151865/HL/NHLBI NIH HHS/United States
R01-HL158668/HL/NHLBI NIH HHS/United States
IO1BX005295/U.S. Department of Veterans Affairs/United States
R01 HL149836/HL/NHLBI NIH HHS/United States
I01 BX005295/BX/BLRD VA/United States
P30 CA046934/CA/NCI NIH HHS/United States
R01-HL149836/HL/NHLBI NIH HHS/United States
UG3 HL151865/HL/NHLBI NIH HHS/United States
UG3/UH3 HL151865/HL/NHLBI NIH HHS/United States
P01 HL162607/HL/NHLBI NIH HHS/United States