[Effects of gender on pulmonary rehabilitation outcomes in patients with COPD]

Rev Mal Respir. 2024 Sep;41(7):463-471. doi: 10.1016/j.rmr.2024.06.007. Epub 2024 Jun 29.
[Article in French]

Abstract

Introduction: COPD has become more prevalent among women, revealing a specific feminine phenotype. Women experience greater dyspnea and a more impaired quality of life. The main objective of this study was to assess the effect of gender on dyspnea during a pulmonary rehabilitation program (PRP).

Methods: Retrospective study including COPD patients having participated in PRPs. The following data were analyzed according to gender before and after a PRP: dyspnea, quality of life, anxiety and depression, exercise capacity, muscle function (quadriceps and inspiratory muscles).

Results: More than 500 patients (252 men and 252 women) were included. We did not find a significant effect of gender on the evolution of dyspnea, anxiety or depressive disorders, exercise capacity, inspiratory muscle strength, or overall quality of life score. That said, we found a possible effect on the sub-scores of the quality of life questionnaire, and regarding quadriceps strength. All criteria improved during the program in both groups.

Conclusions: During a PRP, gender does not impact the evolution of dyspnea. While women may nonetheless benefit to a greater extent in terms of quality of life sub-scores (impact, activities, symptoms) and quadriceps strength, these results still require confirmation.

Keywords: Broncho-pneumopathie obstructive chronique; Chronic obstructive pulmonary disease; Dyspnea; Dyspnée; Gender; Genre; Pulmonary rehabilitation; Quality of life; Qualité de vie; Réadaptation respiratoire.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Depression / epidemiology
  • Depression / etiology
  • Depression / psychology
  • Depression / rehabilitation
  • Dyspnea* / etiology
  • Dyspnea* / rehabilitation
  • Exercise Tolerance / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength / physiology
  • Pulmonary Disease, Chronic Obstructive* / complications
  • Pulmonary Disease, Chronic Obstructive* / psychology
  • Pulmonary Disease, Chronic Obstructive* / rehabilitation
  • Quality of Life*
  • Retrospective Studies
  • Sex Factors
  • Treatment Outcome