Perifollicular Melanocyte Regeneration in Bullous Pemphigoid

Cureus. 2024 Jun 4;16(6):e61652. doi: 10.7759/cureus.61652. eCollection 2024 Jun.

Abstract

Bullous pemphigoid (BP) is an autoimmune skin disorder that causes fluid-filled blisters to appear on various body parts, often preceded by urticaria and pruritis. This case report describes the perifollicular melanocyte regeneration within diseased areas in a skin of color patient with BP. By reviewing the various pathologies that can result in melanocyte destruction and the basic science of melanocyte regeneration, we can better identify and explain this phenomenon to patients and lead to earlier diagnoses. Furthermore, due to the lack of published information on skin conditions in skin of color patients, this report can assist in raising awareness of an atypical BP presentation in the dermatological community.

Keywords: bullous pemphigoid; bullous skin disease; clinical dermatology; melanocyte; skin of color.

Publication types

  • Case Reports