High phosphate-induced JAK-STAT signalling sustains Vascular Smooth Muscle Cells inflammation and limits calcification

Vascul Pharmacol. 2024 Jun:155:107328. doi: 10.1016/j.vph.2024.107328.
No abstract available

MeSH terms

  • Animals
  • Humans
  • Inflammation / metabolism
  • Inflammation / pathology
  • Janus Kinases / metabolism
  • Muscle, Smooth, Vascular* / drug effects
  • Muscle, Smooth, Vascular* / metabolism
  • Muscle, Smooth, Vascular* / pathology
  • Myocytes, Smooth Muscle* / drug effects
  • Myocytes, Smooth Muscle* / metabolism
  • Myocytes, Smooth Muscle* / pathology
  • Phosphates / metabolism
  • STAT Transcription Factors / metabolism
  • Signal Transduction*
  • Vascular Calcification* / metabolism
  • Vascular Calcification* / pathology

Substances

  • Phosphates
  • Janus Kinases
  • STAT Transcription Factors