Cranial hypertrophic pachymeningitis with myelodysplastic syndrome

Shohei Kikuchi; Tomohiro Hayashi; Honoka Nitta; Yusuke Kamihara; Akinori Wada; Tomoki Minemura; Yoshimi Nabe; Jun Murakami; Yuji Nakatsuji; Tsutomu Sato

doi:10.1016/j.heliyon.2024.e32973

Cranial hypertrophic pachymeningitis with myelodysplastic syndrome

Heliyon. 2024 Jun 13;10(12):e32973. doi: 10.1016/j.heliyon.2024.e32973. eCollection 2024 Jun 30.

Authors

Affiliations

¹ Department of Hematology, Toyama University Hospital, Toyama, Japan.
² Department of Neurology, Toyama University Hospital, Toyama, Japan.
³ Department of Clinical Laboratory and Blood Center, Toyama University Hospital, Toyama, Japan.
⁴ Division of Transfusion Medicine and Cell Therapy, Toyama University Hospital, Toyama, Japan.

Abstract

Hypertrophic pachymeningitis (HP) is a rare inflammatory disease characterized by thickening of the dura mater. HP develops with several inflammatory diseases. Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and IgG4 related disease are reported as 2 major causes. With hematologic diseases, only 3 cases have been reported. We report the case of myelodysplastic syndrome (MDS) developing HP. Our case provides a thought-provoking hypothesis regarding the potential relationship between MDS and HP.

Keywords: Hypertrophic pachymeningitis; Myelodysplastic syndrome; Steroids therapy.

Publication types

Case Reports