The correlation between corona virus disease 2019 and alopecia areata: a literature review

Front Immunol. 2024 Jul 3:15:1347311. doi: 10.3389/fimmu.2024.1347311. eCollection 2024.

Abstract

Corona virus disease 2019(COVID-19) is one of the most serious respiratory pandemic diseases threatening human health for centuries. Alopecia areata (AA) is a sudden patchy hair loss, an autoimmune disease, which seriously affects the image and mental health of patients. Evidence shows that the risk of autoimmune diseases significantly increases after COVID-19, and is positively correlated with the severity, with a significant increase in the risk of alopecia in those over 40 years old. The relationship between COVID-19 and AA has become a hot topic of current research. Strengthening the research on the correlation between COVID-19 and AA can help to identify and protect susceptible populations at an early stage. This article reviews the research progress on the epidemiological background of COVID-19 and AA, the situation and possible mechanisms of AA induced by COVID-19 or COVID-19 vaccination, and potential treatment methods.

Keywords: COVID-19; alopecia areata; correlation; pathogenesis; treatment; vaccination.

Publication types

  • Review

MeSH terms

  • Alopecia Areata* / epidemiology
  • Alopecia Areata* / immunology
  • COVID-19 Vaccines / immunology
  • COVID-19* / epidemiology
  • COVID-19* / immunology
  • Humans
  • SARS-CoV-2* / immunology

Substances

  • COVID-19 Vaccines

Grants and funding

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.