Evaluation of the DxU 850m Iris automated urine microscopy analyzer for identifying culture-negative urine samples: From a perspective of reducing urine culture number

Kristian Stærk; Ziyap Acar; Jan Berg Gertsen; Ulrik S Justesen

doi:10.1016/j.diagmicrobio.2024.116439

Evaluation of the DxU 850m Iris automated urine microscopy analyzer for identifying culture-negative urine samples: From a perspective of reducing urine culture number

Diagn Microbiol Infect Dis. 2024 Sep;110(1):116439. doi: 10.1016/j.diagmicrobio.2024.116439. Epub 2024 Jul 11.

Authors

Kristian Stærk¹, Ziyap Acar², Jan Berg Gertsen³, Ulrik S Justesen⁴

Affiliations

¹ Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense Denmark. Electronic address: kristian.staerk@rsyd.dk.
² Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
³ Department of Clinical Microbiology, Aarhus University Hospital, Århus, Denmark.
⁴ Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense Denmark.

PMID: 39024934
DOI: 10.1016/j.diagmicrobio.2024.116439

Abstract

We evaluated the DxU 850m Iris Urine Microscopy analyzer as a screening tool for excluding negative urine samples (n = 1337). At a cutoff of 10³ colony counts·mL^-1, sensitivity was 55.1 %, specificity 68.6 %. The DxU 850m Iris does not offer acceptable prediction of culture-negative urine samples at the tested cutoff.

Keywords: Bacteriuria screening; DxU 850 Iris; Urinalysis; Urinary tract infection; Urine culture.

Publication types

Evaluation Study

MeSH terms

Automation, Laboratory / methods
Humans
Microscopy* / methods
Sensitivity and Specificity*
Urinalysis* / instrumentation
Urinalysis* / methods
Urinary Tract Infections / diagnosis
Urinary Tract Infections / microbiology
Urine* / microbiology