Infection Rates in Clean Surgical Procedures: A Comparison of Ampicillin Prophylaxis vs a Placebo

J Am Vet Med Assoc. 1985 Oct 15;187(8):825-7.


A total of 122 dogs and 7 cats were included in a prospective, randomized, blind trial to determine the frequency of wound infection after clean surgical procedures and to compare the infection rates in dogs and cats given ampicillin (group 1) with those given a placebo (group 2). The 2 groups were similar in terms of mean age, sex ratio, duration of hospital stay, and types of surgical procedures. A wound infection developed in one of the dogs given ampicillin; there were no wound infections in the animals given the placebo. The infection rates in the 2 groups were not significantly different.

Publication types

  • Clinical Trial

MeSH terms

  • Ampicillin / therapeutic use*
  • Animals
  • Cats
  • Clinical Trials as Topic
  • Dogs
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Premedication
  • Random Allocation
  • Surgical Wound Infection / prevention & control*


  • Ampicillin