Abstract
Eighty-one patients with atopic dermatitis and contact dermatitis received a 1-week treatment with 0.1% betamethasone alone on one side and 0.1% betamethasone plus 2% fusidic acid on the other side. Clinically, the combination was marginally superior and in patient preference a significant difference in favour of the combination was recorded. Bacteriologically, the combination eliminated 67% of bacteria originally present in the skin lesions compared with 51% with steroid alone.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Betamethasone / administration & dosage
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Betamethasone / adverse effects
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Betamethasone / therapeutic use*
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Clinical Trials as Topic
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Double-Blind Method
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Drug Resistance, Microbial
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Drug Therapy, Combination
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Eczema / complications
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Eczema / drug therapy*
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Eczema / microbiology
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Female
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Fusidic Acid / administration & dosage
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Fusidic Acid / adverse effects
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Fusidic Acid / therapeutic use*
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Humans
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Male
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Middle Aged
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Random Allocation
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Skin Diseases, Infectious / drug therapy*
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Skin Diseases, Infectious / etiology
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Staphylococcal Infections / drug therapy
Substances
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Fusidic Acid
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Betamethasone