Vaccination and herd immunity to infectious diseases

Nature. 1985 Nov 28-Dec 4;318(6044):323-9. doi: 10.1038/318323a0.


An understanding of the relationship between the transmission dynamics of infectious agents and herd immunity provides a template for the design of effective control programmes based on mass immunization. Mathematical models of the spread and persistence of infection provide important insights into the problem of how best to protect the community against disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Age Factors
  • Communicable Disease Control*
  • Communicable Diseases / immunology*
  • Developing Countries
  • Disease Outbreaks / prevention & control
  • Humans
  • Models, Theoretical
  • Periodicity
  • Vaccination*