Neuropeptide Y and peptide YY neuronal and endocrine systems

Peptides. 1985 Jul-Aug;6(4):755-68. doi: 10.1016/0196-9781(85)90180-9.


An extensive system of neuropeptide Y (NPY) containing neurons has recently been identified in the central and peripheral nervous system. In addition, NPY and a structurally related peptide, peptide YY (PYY), containing endocrine cells have been identified in the periphery. The NPY system is of particular interest as the peptide coexists with catecholamines in the central and sympathetic nervous system and adrenal medulla. Evidence has been presented which indicates that NPY may play important roles in regulating autonomic function.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / physiology
  • Brain / ultrastructure
  • Endocrine Glands / physiology*
  • Gastrointestinal Hormones / physiology*
  • Nerve Tissue Proteins / analysis
  • Nerve Tissue Proteins / physiology*
  • Neurons / physiology*
  • Neuropeptide Y
  • Peptide YY
  • Peptides / analysis
  • Peptides / physiology*
  • Sympathetic Nervous System / cytology
  • Sympathetic Nervous System / physiology
  • Tissue Distribution


  • Gastrointestinal Hormones
  • Nerve Tissue Proteins
  • Neuropeptide Y
  • Peptides
  • Peptide YY