The effect of sodium bicarbonate mini-tablets ingested in a carbohydrate hydrogel system on 40 km cycling time trial performance and metabolism in trained male cyclists

Eur J Appl Physiol. 2024 Dec;124(12):3671-3682. doi: 10.1007/s00421-024-05567-3. Epub 2024 Jul 28.

Abstract

Introduction: Sodium bicarbonate (NaHCO3) ingestion has been found to be ergogenic in high-intensity exercise that ranges from 1 to 10 min; however, limited studies have investigated high-intensity exercise beyond this duration.

Purpose: The present study aimed to determine the effect of NaHCO3 ingested using a carbohydrate hydrogel delivery system on 40 km time trial (TT) performance in trained male cyclists.

Methods: Fourteen trained male cyclists ingested 0.3 g kg-1 BM NaHCO3 (Maurten AB, Sweden) to determine individualised peak alkalosis, which established time of ingestion prior to exercise. Participants completed a 40 km familiarisation TT, and two 40 km experimental TTs after ingestion of either NaHCO3 or placebo in a randomised, double-blind, crossover design.

Results: NaHCO3 supplementation improved performance (mean improvement = 54.14 s ± 18.16 s; p = 0.002, g = 0.22) and increased blood buffering capacity prior to (HCO3- mean increase = 5.6 ± 0.2 mmol L-1, p < 0.001) and throughout exercise (f = 84.82, p < 0.001, pη2 = 0.87) compared to placebo. There were no differences in total gastrointestinal symptoms (GIS) between conditions either pre- (NaHCO3, 22 AU; Placebo, 44 AU; p = 0.088, r = 0.46) or post-exercise (NaHCO3, 76 AU; Placebo, 63 AU; p = 0.606, r = 0.14).

Conclusion: The present study suggests that ingesting NaHCO3 mini-tablets in a carbohydrate hydrogel can enhance 40 km TT performance in trained male cyclists, with minimal GIS. This ingestion strategy could therefore be considered by cyclists looking for a performance enhancing ergogenic aid.

Keywords: Alkalosis; Ergogenic aid; Extracellular buffering; High intensity exercise.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Athletic Performance* / physiology
  • Bicycling* / physiology
  • Cross-Over Studies
  • Dietary Carbohydrates / administration & dosage
  • Dietary Carbohydrates / pharmacology
  • Double-Blind Method
  • Humans
  • Hydrogels*
  • Male
  • Performance-Enhancing Substances / administration & dosage
  • Performance-Enhancing Substances / pharmacology
  • Sodium Bicarbonate* / administration & dosage
  • Sodium Bicarbonate* / pharmacology
  • Tablets

Substances

  • Sodium Bicarbonate
  • Hydrogels
  • Performance-Enhancing Substances
  • Tablets
  • Dietary Carbohydrates