Effect of ketotifen treatment on cold-induced urticaria

Ann Allergy. 1985 Dec;55(6):840-3.

Abstract

Eleven patients with primary acquired cold-induced urticaria were treated with ketotifen (1 mg b.i.d.) or placebo in a double-blind, crossover design trial. After seven days of ketotifen treatment, reaction times to a cold stimulus were significantly delayed in ten of the 11 subjects. No effect was seen after placebo treatment. It is concluded that ketotifen may have a place in the treatment of primary acquired cold urticaria.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Clinical Trials as Topic
  • Cold Temperature / adverse effects
  • Double-Blind Method
  • Female
  • Humans
  • Ketotifen / therapeutic use*
  • Male
  • Middle Aged
  • Placebos
  • Time Factors
  • Urticaria / etiology
  • Urticaria / prevention & control*

Substances

  • Placebos
  • Ketotifen