Need for sex-stratified reference values for exhaled nitric oxide as biomarker in chronic cough

Sebastian Riemann; Johnmary T Arinze; Andrei Malinovschi; Guy G Brusselle

doi:10.1183/23120541.00202-2024

Need for sex-stratified reference values for exhaled nitric oxide as biomarker in chronic cough

ERJ Open Res. 2024 Jul 29;10(4):00202-2024. doi: 10.1183/23120541.00202-2024. eCollection 2024 Jul.

Authors

Sebastian Riemann^{1

2

3}, Johnmary T Arinze⁴, Andrei Malinovschi⁵, Guy G Brusselle^{1

2

3}

Affiliations

¹ Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
² Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
³ Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
⁴ Department of Medical Informatics, Erasmus Medical Center, Rotterdam, the Netherlands.
⁵ Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.

Abstract

The implementation of exhaled nitric oxide fraction (F _ENO) as a biomarker in patients with chronic cough requires sex-stratified F _ENO reference values in general and sex-stratified cut-off levels in the management of unexplained chronic cough https://bit.ly/3JHi0vb.