In this study, three different ecotypes of M. longifolia collected from Lorestan province, Iran. three habitats including Khorramabad (ecotype 1), Aleshtar (ecotype 2), and Delfan (ecotype 3) counties (ecotype 3) were selected. In addition to analysing the chemical composition of the essential oils, for the first time, the effects of essential oils of these ecotypes against plant pathogenic bacterial including Erwinia amylovora and Pseudomonas syringae together with Bacillus subtilis, a biocontrol agent, and viability of colon tumour cell (SW742) was evaluated. Results showed that ecotype 1 had the highest concentration of the essential oil. All three bacteria showed the same level of sensitivity to the essential oils of M. longifolia extracted from three different ecotypes. Considering the findings of the effects of essential oils on SW742 tumour cell viability, we can suggest that M. longifolia essential oil obtained from ecotype 3 can be used to reduce the cell viability of SW742 tumour cells. It can be concluded that M. longifolia essential oil can be used to reduce tumour cell viability and their anti-microbial activity against plant pathogens.
Keywords: Mentha longifolia; anti-cancer; essential oil; plant pathogens.