Synaptic fidelity for drug development: is it time to move beyond glutamate release and receptors?

Expert Opin Ther Targets. 2024 Aug;28(8):651-653. doi: 10.1080/14728222.2024.2389201. Epub 2024 Aug 6.
No abstract available

Keywords: MRS; NMDA; density; energy per cycle; glutamate; ketamine; schizophrenia; strength; synaptic fidelity.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Drug Development*
  • Glutamic Acid* / metabolism
  • Humans
  • Receptors, Glutamate* / metabolism
  • Synapses / metabolism

Substances

  • Glutamic Acid
  • Receptors, Glutamate