Clinical outcomes after topography-guided FS-LASIK for myopia with nonastigmatic eyes

BMC Ophthalmol. 2024 Aug 5;24(1):325. doi: 10.1186/s12886-024-03593-5.

Abstract

Background: To analyze the clinical outcomes after topography-guided femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) with Phorcides Analytic Engine (PAE) algorithm or Custom-Q FS-LASIK for myopia with nonastigmatic eyes.

Methods: In this retrospective study, a total of 90 eyes with myopia without manifest astigmatism (82 patients) were included. All surgeries were performed by topography-guided FS-LASIK planned with a PAE algorithm (42 eyes) or Custom-Q system (48 eyes). Refractive, visual outcomes and corneal aberrations were compared between the two groups.

Results: At 6 months postoperatively, the postoperative uncorrected distance visual acuity (UDVA) was 20/20 or better in 42 eyes (100%) in the PAE compared with 44 eyes (92%) in Custom-Q (P = .120). The postoperative UDVA of 20/16 or better was measured in 92% of eyes in the PAE group and 81% of eyes in the Custom Q group (P = .320). Postoperative corrected distance visual acuity, manifest refractive spherical equivalent and refractive astigmatism were similar between the two groups (P > .05). The postoperative optical path difference (OPD) and Strehl ratio (SR) were significantly better in the PAE group compared with the Custom Q group.

Conclusions: Topography-guided FS-LASIK with PAE algorithm or Custom Q demonstrated similar refractive efficacy and predictability. PAE for the patients with zero manifest astigmatism demonstrated better results in correcting corneal aberrations.

Keywords: FS-LASIK; Nonastigmatic eyes; Topography-guided.

MeSH terms

  • Adult
  • Corneal Topography*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ* / methods
  • Lasers, Excimer* / therapeutic use
  • Male
  • Myopia* / physiopathology
  • Myopia* / surgery
  • Refraction, Ocular* / physiology
  • Retrospective Studies
  • Surgery, Computer-Assisted / methods
  • Treatment Outcome
  • Visual Acuity* / physiology
  • Young Adult