Estimating the Impact of Tuberculosis Pathways on Transmission-What Is the Gap Left by Passive Case Finding?

Katherine C Horton; Ty McCaffrey; Alexandra S Richards; Alvaro Schwalb; Rein M G J Houben

doi:10.1093/infdis/jiae390

Estimating the Impact of Tuberculosis Pathways on Transmission-What Is the Gap Left by Passive Case Finding?

J Infect Dis. 2024 Nov 15;230(5):e1158-e1161. doi: 10.1093/infdis/jiae390.

Authors

Katherine C Horton^{1

2}, Ty McCaffrey^{1

2}, Alexandra S Richards^{1

2}, Alvaro Schwalb^{1

2

3}, Rein M G J Houben^{1

2}

Affiliations

¹ TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, United Kingdom.
² Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom.
³ Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.

Abstract

Current passive case-finding policies have not resulted in the expected decline in tuberculosis incidence. Recognition of the variety of disease pathways experienced by individuals with tuberculosis highlights how many are not served by the current prevention and care system and how much transmission is missed.

Keywords: detection; dynamics; subclinical; transmission; tuberculosis.

MeSH terms

Humans
Incidence
Tuberculosis* / epidemiology
Tuberculosis* / transmission

Grants and funding

UK government