Mind-body exercise for patients with stable COPD on lung function and exercise capacity: a systematic review and meta-analysis of RCTs

Sci Rep. 2024 Aug 7;14(1):18300. doi: 10.1038/s41598-024-69394-4.

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a global health concern. Mind-body exercises like Tai Chi and Yoga are suggested as non-pharmacological interventions for COPD management. This meta-analysis evaluates mind-body exercises' impact on lung function and exercise capacity in stable COPD patients, aiming to assess their effectiveness in rehabilitation. A systematic search across various databases identified relevant randomized controlled trials until April 2024. Primary outcomes included lung function tests (FEV1, FVC, FEV1/FVC, FEV1%) and Six-Minute Walk Test (6MWT) results. The Standardized Mean Difference (SMD) measured intervention effects. Fifteen studies with 1047 participants were analyzed. Mind-body exercises significantly improved FEV1 (SMD = 0.87), FEV1/FVC (SMD = 0.19), FEV1% (SMD = 0.43), and 6MWT (SMD = 1.21) compared to standard care. Sensitivity and subgroup analyses confirmed result stability despite some heterogeneity.In conclusion, Mind-body exercises enhance lung function and exercise capacity in stable COPD patients. Integrating them into comprehensive rehabilitation programs is advisable. Further research should explore the specific impacts of different exercise types and intensities.

Keywords: Chronic obstructive pulmonary disease; Exercise capacity; Lung function; Meta-analysis; Mind–body exercises.

Publication types

  • Systematic Review
  • Meta-Analysis

MeSH terms

  • Exercise Therapy / methods
  • Exercise Tolerance / physiology
  • Humans
  • Lung / physiopathology
  • Mind-Body Therapies / methods
  • Pulmonary Disease, Chronic Obstructive* / physiopathology
  • Pulmonary Disease, Chronic Obstructive* / rehabilitation
  • Randomized Controlled Trials as Topic*
  • Respiratory Function Tests
  • Tai Ji / methods
  • Yoga