Abstract
An outbreak of influenza A (H5N1) virus was detected in dairy cows in the United States. We detected influenza A virus sialic acid -α2,3/α2,6-galactose host receptors in bovine mammary glands by lectin histochemistry. Our results provide a rationale for the high levels of H5N1 virus in milk from infected cows.
Keywords:
United States; cattle; host tropism; influenza; influenza A virus; receptor; sialic acid; viruses.
MeSH terms
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Animals
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Birds / virology
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Cattle
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Cattle Diseases / virology
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Female
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Humans
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Influenza A Virus, H5N1 Subtype
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Influenza in Birds / epidemiology
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Influenza in Birds / virology
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Influenza, Human / virology
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Mammary Glands, Animal* / virology
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Milk / virology
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Orthomyxoviridae Infections* / veterinary
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Orthomyxoviridae Infections* / virology
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Receptors, Cell Surface / metabolism
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Receptors, Virus* / metabolism
Substances
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Receptors, Virus
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Receptors, Cell Surface