First birth after uterine transposition in low-volume lymph node metastasis of cervical cancer: A long journey for success

J Surg Oncol. 2024 Sep;130(4):896-903. doi: 10.1002/jso.27805. Epub 2024 Aug 13.

Abstract

Locally advanced cervical cancer poses a significant challenge to fertility-sparing treatments. Pelvic radiotherapy impairs reproductive potential owing to ovarian, uterine, and endometrial side effects. This study presents a literature review of the main fertility-sparing therapeutic alternatives for locally advanced cervical cancer and a case report of the first childbirth following uterine transposition for gynecological malignancies.

Keywords: cervical cancer; fertility‐sparing; low‐volume lymph node metastasis; reproductive and obstetrics outcomes; uterine transposition.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Fertility Preservation / methods
  • Humans
  • Lymphatic Metastasis*
  • Pregnancy
  • Uterine Cervical Neoplasms* / pathology
  • Uterine Cervical Neoplasms* / therapy
  • Uterus* / pathology