Response to PARP Inhibition in BARD1-Mutated Refractory Neuroblastoma

MeSH terms

• Bone Marrow Neoplasms* / secondary
• Bone Marrow Neoplasms* / therapy
• Chemoradiotherapy, Adjuvant / methods
• Child, Preschool
• Drug Resistance, Neoplasm / genetics
• Female
• Germ-Line Mutation
• Humans
• Neoplasm Recurrence, Local* / drug therapy
• Neoplasm Recurrence, Local* / genetics
• Neuroblastoma* / genetics
• Neuroblastoma* / pathology
• Neuroblastoma* / therapy
• Phthalazines* / therapeutic use
• Piperazines / therapeutic use
• Poly(ADP-ribose) Polymerase Inhibitors* / therapeutic use
• Treatment Outcome
• Tumor Suppressor Proteins* / genetics
• Ubiquitin-Protein Ligases* / genetics