Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

JAMA Neurol. 2024 Oct 1;81(10):1023-1024. doi: 10.1001/jamaneurol.2024.2464.
No abstract available

Plain language summary

This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.

MeSH terms

  • Alzheimer Disease* / metabolism
  • Animals
  • Humans
  • Parkinson Disease* / metabolism
  • Prion Diseases / metabolism
  • Prions / metabolism

Substances

  • Prions