The moyamoya syndrome associated with irradiation of an optic glioma in children: report of two cases and review of the literature

Pediatr Neurol. Sep-Oct 1985;1(5):311-6. doi: 10.1016/0887-8994(85)90036-0.

Abstract

We report two cases of the moyamoya syndrome which became clinically apparent after irradiation of an optic glioma during childhood. A summary of 14 cases of this syndrome following irradiation of intracranial tumors is also presented. Nine of these cases were optic gliomas; five were found in children with neurofibromatosis, another disorder that has a strong association with the moyamoya syndrome. The effectiveness of irradiation of optic gliomas in childhood is not definitely established. The possibility of inducing serious vascular disease is a further reason for caution when considering irradiating these tumors.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Arterial Occlusive Diseases / etiology*
  • Cerebral Arteries / radiation effects*
  • Cranial Nerve Neoplasms / radiotherapy*
  • Female
  • Follow-Up Studies
  • Glioma / radiotherapy*
  • Humans
  • Moyamoya Disease / etiology*
  • Optic Nerve Diseases / radiotherapy*
  • Radiation Injuries / etiology*