Age-related variations in stratum corneum hydration in the foot

Maturitas. 2024 Nov:189:108104. doi: 10.1016/j.maturitas.2024.108104. Epub 2024 Aug 22.

Abstract

Objective: The aims of the study are to identify which region of the foot has lower hydration according to age, measure the variation in the level of stratum corneum hydration of the foot across the a wide age range, and examine hydration differences of the foot according to gender.

Study design: A descriptive observational study was conducted to assess stratum corneum hydration of the foot among 504 participants recruited between November 2023 and March 2024.

Main outcomes measures: Stratum corneum hydration assessment was conducted using a Corneometer 825® probe at 10 specific points on the foot. Data on sociodemographic variables, medical history, foot care habits, and hydration-related factors were collected. Statistical analyses were performed using SPSS v. 24.0.

Results: Stratum corneum hydration of the foot varied significantly across regions, with higher hydration in the digital zone and lower hydration in the heel. An inverse correlation was found between age and hydration, with younger participants exhibiting higher hydration levels. Women showed higher hydration than men. Differences in hydration were observed between the right and left feet.

Conclusion: This study highlights the importance of localized assessment of foot skin dehydration. Aging significantly affects stratum corneum hydration of the foot. Gender differences in hydration suggest the importance of personalized approaches to skin care. Differential hydration between feet underscores the influence of mechanical load.

Keywords: Aging; Corneometer; Stratum corneum hydration.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging / physiology
  • Dehydration / physiopathology
  • Epidermis / metabolism
  • Epidermis / physiology
  • Female
  • Foot*
  • Humans
  • Male
  • Middle Aged
  • Sex Factors
  • Young Adult