Assessment of accuracy and repeatability of quantitative parameter mapping in MRI

Yuya Hirano; Kinya Ishizaka; Hiroyuki Sugimori; Yo Taniguchi; Tomoki Amemiya; Yoshitaka Bito; Kohsuke Kudo

doi:10.1007/s12194-024-00836-4

Assessment of accuracy and repeatability of quantitative parameter mapping in MRI

Radiol Phys Technol. 2024 Dec;17(4):918-928. doi: 10.1007/s12194-024-00836-4. Epub 2024 Aug 28.

Authors

Yuya Hirano¹, Kinya Ishizaka¹, Hiroyuki Sugimori^{2

3}, Yo Taniguchi⁴, Tomoki Amemiya⁴, Yoshitaka Bito^{5

6}, Kohsuke Kudo^{7

8}

Affiliations

¹ Department of Radiological Technology, Hokkaido University Hospital, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
² Faculty of Health Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
³ Clinical AI Human Resources Development Program, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, 060-8648, Japan.
⁴ Medical Systems Research & Development Center, FUJIFILM Corporation, Tokyo, Japan.
⁵ FUJIFILM Healthcare Corporation, Tokyo, Japan.
⁶ Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
⁷ Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan. kkudo@med.hokudai.ac.jp.
⁸ Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan. kkudo@med.hokudai.ac.jp.

Abstract

We aimed to evaluate the accuracy and repeatability of the T1, T2*, and proton density (PD) values obtained by quantitative parameter mapping (QPM) using the ISMRM/NIST MRI system phantom and compared them with computer simulations. We compared the relaxation times and PD obtained through QPM with the reference values of the ISMRM/NIST MRI system phantom and conventional methods. Furthermore, we evaluated the presence or absence of influences other than noise in T1 and T2* values obtained by QPM by comparing the obtained coefficient of variation (CV) with simulation results. The T1, T2*, and PD values by QPM showed a strong correlation with the measured values and the referenced values. The simulated CVs of QPM calculated for each sphere showed similar trends to those of the actual scans.

Keywords: Bloch simulation; Magnetic resonance imaging; Multi-parameter mapping; Relaxation time.

MeSH terms

Computer Simulation
Image Processing, Computer-Assisted* / methods
Magnetic Resonance Imaging* / methods
Phantoms, Imaging*
Reproducibility of Results