Using real-world evidence to complement evidence from randomized controlled trials on oral anticoagulants for stroke prevention

Mark J R Smeets; Suzanne C Cannegieter

doi:10.1371/journal.pmed.1004449

Using real-world evidence to complement evidence from randomized controlled trials on oral anticoagulants for stroke prevention

PLoS Med. 2024 Aug 29;21(8):e1004449. doi: 10.1371/journal.pmed.1004449. eCollection 2024 Aug.

Authors

Mark J R Smeets¹, Suzanne C Cannegieter^{1

2}

Affiliations

¹ Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
² Department of Internal Medicine, section Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands.

Abstract

Mark J. R. Smeets and Suzanne C. Cannegieter discuss the use of real world data to complement data generated by clinical trials of systemic anticoagulants.

Copyright: © 2024 Smeets, Cannegieter. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication types

Comment

MeSH terms

Administration, Oral
Anticoagulants* / administration & dosage
Anticoagulants* / therapeutic use
Atrial Fibrillation / complications
Atrial Fibrillation / drug therapy
Humans
Randomized Controlled Trials as Topic*
Stroke* / prevention & control

Substances

Anticoagulants