Response of CHO cell DNA polymerase alpha to dCTP and dTTP pool imbalance: relation to DNA synthesis inhibition, survival and mutation

Basic Life Sci. 1985;31:127-48. doi: 10.1007/978-1-4613-2449-2_8.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Aphidicolin
  • Cell Line
  • Cell Survival
  • Cricetinae
  • DNA / biosynthesis*
  • DNA / radiation effects
  • DNA Polymerase II / antagonists & inhibitors
  • DNA Polymerase II / metabolism*
  • Deoxycytosine Nucleotides / metabolism*
  • Deoxyribonucleotides / metabolism
  • Diterpenes / pharmacology
  • Drug Resistance
  • Female
  • Methylnitronitrosoguanidine / pharmacology
  • Mutation*
  • Ovary
  • Thymine Nucleotides / metabolism*
  • Ultraviolet Rays

Substances

  • Deoxycytosine Nucleotides
  • Deoxyribonucleotides
  • Diterpenes
  • Thymine Nucleotides
  • Methylnitronitrosoguanidine
  • 2'-deoxycytidine 5'-triphosphate
  • Aphidicolin
  • DNA
  • DNA Polymerase II
  • thymidine 5'-triphosphate