Elimination of mutant SWI/SNF complexes by protein quality control: new opportunities targeting aggressive rhabdoid tumours

Signal Transduct Target Ther. 2024 Sep 6;9(1):224. doi: 10.1038/s41392-024-01935-9.
No abstract available

Publication types

  • Letter

MeSH terms

  • Chromosomal Proteins, Non-Histone / genetics
  • Chromosomal Proteins, Non-Histone / metabolism
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism
  • Humans
  • Mutation
  • Rhabdoid Tumor* / genetics
  • Rhabdoid Tumor* / pathology
  • SMARCB1 Protein / genetics
  • SMARCB1 Protein / metabolism
  • Transcription Factors* / genetics
  • Transcription Factors* / metabolism

Substances

  • Transcription Factors
  • Chromosomal Proteins, Non-Histone
  • SMARCB1 Protein
  • DNA-Binding Proteins
  • SWI-SNF-B chromatin-remodeling complex