Ubiquitylation: Sword and shield in the bacterial arsenal

Mol Cell. 2024 Sep 19;84(18):3378-3380. doi: 10.1016/j.molcel.2024.08.034.

Authors

Jonathan N Pruneda¹, Felix Randow²

Affiliations

¹ Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: pruneda@ohsu.edu.
² MRC Laboratory of Molecular Biology, PNAC Division, Francis Crick Avenue, Cambridge CB20QH, UK; University of Cambridge, Department of Medicine, Addenbrooke's Hospital, Cambridge CB22QQ, UK. Electronic address: randow@mrc-lmb.cam.ac.uk.

PMID: 39303679
DOI: 10.1016/j.molcel.2024.08.034

Abstract

In two recent studies in Nature, Hör et al.¹ and Chambers et al.² report that ubiquitin-like conjugation in bacteria antagonizes phage replication.

Copyright © 2024 Elsevier Inc. All rights reserved.

MeSH terms

Bacteria / genetics
Bacteria / metabolism
Bacteria / virology
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Bacteriophages / metabolism
Bacteriophages / physiology
Ubiquitin / metabolism
Ubiquitination*
Virus Replication

Substances

Ubiquitin
Bacterial Proteins