Gynecomasty: estrogen and androgen receptors. A clinical-pathological investigation

Acta Pathol Microbiol Immunol Scand A. 1985 Sep;93(5):229-33. doi: 10.1111/j.1699-0463.1985.tb03946.x.

Abstract

The histology, estrogen (ER)- and androgen (AR)- receptor content, s-FSH, s-LH, s-17-beta-estradiol, U-17-ketosteroid and U-17-ketogenic steroid patterns were measured in a consecutive series of 20 patients operated on for gynecomasty. Two out of 22 specimens were ER-positive, and 4 out of 22 were AR-positive. No relationship was demonstrated between the histopathologic features, ie. active-intermediate-inactive gynecomasty, and the steroid receptor content in the present limited number of cases. In addition, there was no marked relationship between the histopathologic features and the hormone values.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 17-Hydroxycorticosteroids / analysis
  • 17-Ketosteroids / analysis
  • Adolescent
  • Adult
  • Aged
  • Estradiol / analysis
  • Follicle Stimulating Hormone / analysis
  • Gynecomastia / metabolism
  • Gynecomastia / pathology*
  • Humans
  • Luteinizing Hormone / analysis
  • Male
  • Middle Aged
  • Receptors, Androgen / analysis*
  • Receptors, Estrogen / analysis*

Substances

  • 17-Hydroxycorticosteroids
  • 17-Ketosteroids
  • Receptors, Androgen
  • Receptors, Estrogen
  • Estradiol
  • Luteinizing Hormone
  • Follicle Stimulating Hormone