Use of Antiperspirant Products and Risk of Breast Cancer: A Meta-Analysis of Case-Control Studies

Cancer Invest. 2024 Oct;42(9):782-792. doi: 10.1080/07357907.2024.2405864. Epub 2024 Sep 26.

Abstract

Although several observational studies have reported a link between the use of underarm cosmetic products and the risk of breast cancer, the findings remain inconsistent. This study aimed to investigate these associations using a meta-analysis of observational studies. In the meta-analysis of seven case-control studies, we found no association between the use of underarm antiperspirants or deodorants and the risk of breast cancer (OR = 0.96, 95%CI 0.78-1.17; I2 = 60.0%). Further prospective cohort studies that provide a higher level of evidence are warranted to confirm our findings.

Keywords: Underarm cosmetics; antiperspirants; breast cancer; case-control study; deodorants; meta-analysis.

Publication types

  • Meta-Analysis

MeSH terms

  • Antiperspirants* / adverse effects
  • Breast Neoplasms* / chemically induced
  • Breast Neoplasms* / epidemiology
  • Case-Control Studies
  • Deodorants* / adverse effects
  • Female
  • Humans
  • Risk Factors

Substances

  • Antiperspirants
  • Deodorants