Influence of body position, dry and water swallows, smoking, and alcohol on esophageal acid clearing

Scand J Gastroenterol. 1978;13(3):283-8. doi: 10.3109/00365527809179821.


Esophageal acid clearing in normal subjects was studied in different body positions, with an assessment of reproducibility, after dry and water swallows, after smoking, and after alcohol intake. A significant increase in the number of swallows to raise the distal esophageal pH to 5.0 was found in the head-down position (p less than 0.003), after smoking (p less than 0.003), and after alcohol intake (p less than 0.001). It is proposed that the outcome of the acid-clearing test reflects both the transporting capacity of the esophageal muscles and the production of saliva. The precision of the acid-clearing test is not satisfactory, which makes it unsuitable for use in individual cases. It seems, however, well fitted for evaluation of esophageal acid clearing in larger samples.

MeSH terms

  • Adolescent
  • Adult
  • Alcohol Drinking
  • Deglutition*
  • Esophagus / physiology*
  • Female
  • Humans
  • Hydrochloric Acid*
  • Hydrogen-Ion Concentration
  • Male
  • Posture*
  • Smoking*


  • Hydrochloric Acid