Acidic oral environment's potential contribution to palladium-induced systemic contact dermatitis: Case report

Takeya Adachi; Katsunori Masaki; Kazuyo Sujino; Utako Okata-Karigane; Taro Murakami; Chiaki Takahashi; Shiori Nakayama; Saki Tomiyasu; Masato Asaoka; Hiroki Kabata; Jun Miyata; Hayato Takahashi; Koichi Fukunaga

doi:10.1016/j.jacig.2024.100333

Acidic oral environment's potential contribution to palladium-induced systemic contact dermatitis: Case report

J Allergy Clin Immunol Glob. 2024 Aug 28;3(4):100333. doi: 10.1016/j.jacig.2024.100333. eCollection 2024 Nov.

Authors

Takeya Adachi^{1

2

3

4}, Katsunori Masaki^{1

5}, Kazuyo Sujino², Utako Okata-Karigane^{1

2}, Taro Murakami⁶, Chiaki Takahashi^{1

2}, Shiori Nakayama⁷, Saki Tomiyasu^{1

5}, Masato Asaoka^{1

5}, Hiroki Kabata^{1

5}, Jun Miyata^{1

5}, Hayato Takahashi^{1

2}, Koichi Fukunaga^{1

5}

Affiliations

¹ Keio Allergy Center, Keio University Hospital, Tokyo, Japan.
² Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
³ Keio Frontier Research and Education Collaborative Square (K-FRECS) at Tonomachi, Keio University, Kanagawa, Japan.
⁴ Department of Medical Innovation and Translational Medical Science, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
⁵ Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
⁶ Keio University Hospital Postgraduate Medical Education Center, Tokyo, Japan.
⁷ Department of Dental Medicine, Keio University School of Medicine, Tokyo, Japan.

Abstract

Acidic oral environments may trigger systemic contact dermatitis via ionization of metals, including palladium. A patch test revealed a late delayed positive response to palladium, emphasizing the need for nuanced diagnostic approaches for allergy management.

Keywords: Systemic contact dermatitis; acidic environment; case report; palladium; patch test.

Publication types

Case Reports