CT of neonatal herpes encephalitis

AJNR Am J Neuroradiol. 1985 Sep-Oct;6(5):773-5.


Seven neonates with proven herpes (HSV type 2) encephalitis exhibited a characteristic sequence of findings on cranial computed tomography (CT). The initial CT abnormalities in all infants were fingerlike areas of cortical increased attenuation noted on unenhanced scans obtained 2-30 days after presentation. These usually were accentuated by increased white-matter lucency. Subsequently (more than 30 days after presentation), extensive cerebral destruction, multicystic encephalomalacia, and calcification were seen on follow-up CT scans obtained in five infants.

MeSH terms

  • Brain / diagnostic imaging*
  • Brain / pathology
  • Encephalitis / diagnostic imaging*
  • Encephalitis / etiology
  • Herpes Simplex / diagnostic imaging*
  • Herpes Simplex / etiology
  • Humans
  • Infant
  • Infant, Newborn
  • Retrospective Studies
  • Tomography, X-Ray Computed*