Cardiology Consult for the General Pediatrician after Cardiac Manifestations from a SARS-CoV-2 Infection

Curr Pediatr Rev. 2026;22(1):11-19. doi: 10.2174/0115733963314978240923110844.

Abstract

The novel Coronavirus Disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, created a need for evidence-based guidelines for the evaluation, management, and follow-up after infection. Data have become rapidly available, creating a challenge for medical providers to stay abreast of the ever-evolving recommendations. This article, written collaboratively by pediatric cardiovascular experts, pediatricians, and sports medicine specialists, is focused on SARS-CoV- 2-related pediatric cardiac manifestations. It aims to provide a systematic review of high-yield literature related to all cardiovascular entities as a tool for primary pediatric clinicians to utilize as they consider the cardiac consequences of acute SARS-CoV-2 infection, MIS-C, vaccine-related myocarditis, return-to-play, and long COVID-19 syndrome.

Keywords: COVID-19; MIS-C; Pediatrics; acute SARS-CoV-2; long COVID-19 syndrome.; myocarditis.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • COVID-19* / complications
  • Cardiology
  • Child
  • Heart Diseases* / diagnosis
  • Heart Diseases* / etiology
  • Heart Diseases* / therapy
  • Humans
  • Myocarditis / diagnosis
  • Myocarditis / etiology
  • Myocarditis / therapy
  • Pediatricians
  • Referral and Consultation
  • Return to Sport
  • SARS-CoV-2
  • Systemic Inflammatory Response Syndrome

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related