A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges

Felicia Gomez; Arpad M Danos; Guilherme Del Fiol; Anant Madabhushi; Pallavi Tiwari; Joshua F McMichael; Spyridon Bakas; Jiang Bian; Christos Davatzikos; Elana J Fertig; Jayashree Kalpathy-Cramer; Johanna Kenney; Guergana K Savova; Meliha Yetisgen; Eliezer M Van Allen; Jeremy L Warner; Fred Prior; Malachi Griffith; Obi L Griffith

doi:10.1158/2159-8290.CD-24-1130

A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges

Cancer Discov. 2024 Oct 4;14(10):1774-1778. doi: 10.1158/2159-8290.CD-24-1130.

Authors

Felicia Gomez^#¹, Arpad M Danos^#¹, Guilherme Del Fiol², Anant Madabhushi^{3

4}, Pallavi Tiwari^{5

6}, Joshua F McMichael¹, Spyridon Bakas^{7

8

9

10

11}, Jiang Bian¹², Christos Davatzikos¹³, Elana J Fertig¹⁴, Jayashree Kalpathy-Cramer¹⁵, Johanna Kenney¹⁶, Guergana K Savova^{17

18}, Meliha Yetisgen¹⁹, Eliezer M Van Allen^{20

21

22}, Jeremy L Warner^{23

24}, Fred Prior²⁵, Malachi Griffith¹, Obi L Griffith¹

Affiliations

¹ Department of Medicine, Washington University School of Medicine, St Louis, Missouri.
² Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah.
³ Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia.
⁴ Atlanta Veterans Affairs (VA) Medical Center, Decatur, Georgia.
⁵ Department of Radiology and Biomedical Engineering, University of Wisconsin, Madison, Wisconsin.
⁶ William S. Middleton Memorial Veterans Affairs (VA) Healthcare, Madison, Wisconsin.
⁷ Departments of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
⁸ Departments of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana.
⁹ Departments of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana.
¹⁰ Departments of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
¹¹ Department of Computer Science, Luddy School of Informatics, Computing, and Engineering, Indiana University, Indianapolis, Indiana.
¹² Department of Health Outcomes & Biomedical Informatics, University of Florida, Gainesville, Florida.
¹³ Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
¹⁴ Department of Oncology and Applied Mathematics & Statistics, Johns Hopkins Medicine, Baltimore, Massachusetts.
¹⁵ Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado.
¹⁶ Technology Research Advocacy Partnership, National Cancer Institute, Bethesda, Maryland.
¹⁷ Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
¹⁸ Boston Children's Hospital, Boston, Massachusetts.
¹⁹ Department of Biomedical and Health Informatics, University of Washington, Seattle, Western Australia.
²⁰ Department of Medicine, Dana-Farber Cancer Institute, Harvard School of Medicine, Boston, Massachusetts.
²¹ Broad Institute, Cambridge, Massachusetts.
²² Parker Institute for Cancer Immunotherapy, San Francisco, California.
²³ Departments of Medicine and Biostatistics, Brown University, Providence, Rhode Island.
²⁴ Lifespan Cancer Institute, Rhode Island Hospital, Providence, Rhode Island.
²⁵ Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

^# Contributed equally.

Abstract

People diagnosed with cancer and their formal and informal caregivers are increasingly faced with a deluge of complex information, thanks to rapid advancements in the type and volume of diagnostic, prognostic, and treatment data. This commentary discusses the opportunities and challenges that the society faces as we integrate large volumes of data into regular cancer care.

MeSH terms

Biomedical Research
Humans
Neoplasms* / therapy

Abstract

MeSH terms

Grants and funding