The peptidoglycan of Neisseria gonorrhoeae, with or without O-acetyl groups, contains anhydro-muramyl residues

J Gen Microbiol. 1985 Dec;131(12):3397-400. doi: 10.1099/00221287-131-12-3397.

Abstract

Muramidase digests of alkali-treated SDS-insoluble peptidoglycan from two strains of Neisseria gonorrhoeae were examined. Both strains contained disaccharide peptide monomers that had intramolecular 1,6-anhydro-muramyl ends. In contrast to strain 1L260, in which 50% of the monomer fraction is O-acetylated, the monomer fraction from strain RD5 was completely devoid of O-acetyl groups, as shown by HPLC. Penicillin decreased the O-acetylation of peptidoglycan but did not affect the proportion of anhydro-muramyl residues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylation
  • Chromatography, High Pressure Liquid
  • Muramidase
  • Neisseria gonorrhoeae / analysis*
  • Peptidoglycan / analysis*

Substances

  • Peptidoglycan
  • Muramidase