Sarcoidosis and primary hypogammaglobulinaemia: a report of two cases and a review of the literature

Sarcoidosis. 1985 Sep;2(2):91-5.


We are aware of only four previous cases of Kveim positive sarcoidosis reported in hypogammaglobulinaemic patients and we describe two further patients. Patients with hypogammaglobulinaemia and a sarcoid-like syndrome or sarcoidosis have been reviewed. Similarities between sarcoidosis and a subgroup of late onset primary hypogammaglobulinaemia have been highlighted. It is suggested that sarcoidosis in this patient population is probably commoner than was previously thought, but the association between the two conditions remains unclear.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Agammaglobulinemia / complications*
  • Agammaglobulinemia / therapy
  • Diabetic Ketoacidosis / complications
  • Humans
  • Immunoglobulin G / therapeutic use
  • Kveim Test
  • Lung Diseases / complications*
  • Lung Diseases / therapy
  • Male
  • Sarcoidosis / complications*
  • Sarcoidosis / therapy


  • Immunoglobulin G