HLA-DRB1*01:03 and Severe Ulcerative Colitis
- PMID: 39403737
- PMCID: PMC11480900
- DOI: 10.1001/jama.2024.20429
HLA-DRB1*01:03 and Severe Ulcerative Colitis
Plain language summary
This Danish nationwide genome-wide association study aims to identify biomarkers of severe vs less severe ulcerative colitis.
Conflict of interest statement
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References
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- Goyette P, Boucher G, Mallon D, et al. ; International Inflammatory Bowel Disease Genetics Consortium; Australia and New Zealand IBDGC; Belgium IBD Genetics Consortium; Italian Group for IBD Genetic Consortium; NIDDK Inflammatory Bowel Disease Genetics Consortium; United Kingdom IBDGC; Wellcome Trust Case Control Consortium; Quebec IBD Genetics Consortium . High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nat Genet. 2015;47(2):172-179. doi:10.1038/ng.3176 - DOI - PMC - PubMed
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