Reductive activation of nitroimidazoles in anaerobic microorganisms

Biochem Pharmacol. 1986 Jan 1;35(1):37-41. doi: 10.1016/0006-2952(86)90552-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anaerobiosis
  • Animals
  • Bacteria, Anaerobic / metabolism*
  • Biotransformation
  • Drug Resistance, Microbial
  • Ferredoxins / metabolism
  • Humans
  • Metronidazole / metabolism
  • Metronidazole / therapeutic use
  • Nitroimidazoles / metabolism*
  • Oxidation-Reduction
  • Trichomonas / metabolism
  • Trichomonas Infections / drug therapy

Substances

  • Ferredoxins
  • Nitroimidazoles
  • Metronidazole